InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Aspm

Summary

InnateDB Protein

IDBP-196483.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Aspm

Protein Name

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

Synonyms

Calmbp1; D330028K02Rik; MCPH5; Sha1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000095162

InnateDB Gene

IDBG-196479 (Aspm)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005488	binding
GO:0005515	protein binding

Biological Process

GO:0001764	neuron migration
GO:0002052	positive regulation of neuroblast proliferation
GO:0007283	spermatogenesis
GO:0007420	brain development
GO:0021873	forebrain neuroblast division
GO:0045665	negative regulation of neuron differentiation
GO:0045769	negative regulation of asymmetric cell division
GO:0048477	oogenesis
GO:0048589	developmental growth
GO:0051661	maintenance of centrosome location
GO:0090263	positive regulation of canonical Wnt signaling pathway

Cellular Component

GO:0000922	spindle pole
GO:0030496	midbody

Protein Structure and Domains

PDB ID

MGI:1334448

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR001715 Calponin homology domain
IPR016024 Armadillo-type fold
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00612
PF00307
PF11971

PRINTS

PIRSF

SMART

SM00015
SM00033

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite