Version 5.4
Mus musculus Protein: Dock3
Summary
InnateDB Protein IDBP-196851.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dock3
Protein Name dedicator of cyto-kinesis 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000047652
InnateDB Gene IDBG-196849 (Dock3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0007264 small GTPase mediated signal transduction
GO:0043087 regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2429763
InterPro IPR001452 SH3 domain
IPR010703 Dedicator of cytokinesis C-terminal
IPR011511 Variant SH3 domain
IPR016024 Armadillo-type fold
PFAM PF00018
PF14604
PF06920
PF07653
PRINTS PR00452
PIRSF
SMART SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F8VPQ1
UniProt Splice Variant
Entrez Gene 208869
UniGene Mm.473115
RefSeq NP_700462
MGI ID
MGI Symbol Dock3
OMIM
CCDS CCDS40760
HPRD
IMGT
EMBL AC121608 AC123065 AC147636 AL672070 AL672208
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca