InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fah

Summary

InnateDB Protein

IDBP-197377.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fah

Protein Name

fumarylacetoacetate hydrolase

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032865

InnateDB Gene

IDBG-197375 (Fah)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Mainly in liver and kidney.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004334	fumarylacetoacetase activity
GO:0046872	metal ion binding

Biological Process

GO:0006527	arginine catabolic process
GO:0006559	L-phenylalanine catabolic process
GO:0006572	tyrosine catabolic process
GO:0008152	metabolic process
GO:0009072	aromatic amino acid family metabolic process

Cellular Component

GO:0070062

extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:95482

InterPro

IPR002529 Fumarylacetoacetase, C-terminal
IPR005959 Fumarylacetoacetase
IPR011234 Fumarylacetoacetase, C-terminal-related
IPR015377 Fumarylacetoacetase, N-terminal

PFAM

PF01557
PF09298

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P35505

PhosphoSite