Version 5.4
Mus musculus Protein: Galns
Summary
InnateDB Protein IDBP-197755.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Galns
Protein Name galactosamine (N-acetyl)-6-sulfate sulfatase
Synonyms mFLJ00319;
Species Mus musculus
Ensembl Protein ENSMUSP00000015171
InnateDB Gene IDBG-197753 (Galns)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Lysosome {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed. Higher expression in liver and kidney. {ECO:0000269PubMed:10699374}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0008484 sulfuric ester hydrolase activity
GO:0043890 N-acetylgalactosamine-6-sulfatase activity
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005764 lysosome
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1355303
InterPro IPR000917 Sulfatase
IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
IPR017850 Alkaline-phosphatase-like, core domain
PFAM PF00884
PF01663
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q571E4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 50917
UniGene Mm.34702
RefSeq NP_057931
MGI ID
MGI Symbol Galns
OMIM
CCDS CCDS40504
HPRD
IMGT
EMBL AF111346 AF112230 AF112231 AF112232 AF112233 AF112234 AF112235 AF112236 AF112237 AF112238 AF112239 AF112240 AF112241 AF112242 AK159592 AK220245 BC004002
GenPept AAF63155 AAF63858 AAH04002 BAD90170 BAE35212

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca