InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dhx9

Summary

InnateDB Protein

IDBP-199047.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dhx9

Protein Name

DEAH (Asp-Glu-Ala-His) box polypeptide 9

Synonyms

AI326842; Ddx9; HEL-5; mHEL-5; NDHII; RHA;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000038135

InnateDB Gene

IDBG-199045 (Dhx9)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 151 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	151 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001085	RNA polymerase II transcription factor binding
GO:0003676	nucleic acid binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0001649	osteoblast differentiation
GO:0006200	ATP catabolic process
GO:0007623	circadian rhythm
GO:0034605	cellular response to heat
GO:0070934	CRD-mediated mRNA stabilization

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005813	centrosome
GO:0016020	membrane
GO:0030529	ribonucleoprotein complex
GO:0036464	cytoplasmic ribonucleoprotein granule
GO:0070937	CRD-mediated mRNA stability complex

Protein Structure and Domains

PDB ID

MGI:108177

InterPro

IPR001650 Helicase, C-terminal
IPR007502 Helicase-associated domain
IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR011709 Domain of unknown function DUF1605
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014720 Double-stranded RNA-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF04408
PF00270
PF07717
PF00035

PRINTS

PIRSF

SMART

SM00490
SM00847
SM00487
SM00358

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite