Version 5.4
Mus musculus Protein: B4galt7
Summary
InnateDB Protein IDBP-199530.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B4galt7
Protein Name xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000098327
InnateDB Gene IDBG-156473 (B4galt7)
Protein Structure
UniProt Annotation
Function Required for the biosynthesis of the tetrasaccharide linkage region of proteoglycans, especially for small proteoglycans in skin fibroblasts. {ECO:0000250}.
Subcellular Localization Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Cis cisternae of Golgi stack. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
GO:0008378 galactosyltransferase activity
GO:0030145 manganese ion binding
GO:0046525 xylosylprotein 4-beta-galactosyltransferase activity
Biological Process
GO:0006024 glycosaminoglycan biosynthetic process
GO:0006029 proteoglycan metabolic process
GO:0006487 protein N-linked glycosylation
GO:0043206 extracellular fibril organization
GO:0048147 negative regulation of fibroblast proliferation
Cellular Component
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
Protein Structure and Domains
PDB ID MGI:2384987
InterPro IPR003859 Beta-1,4-galactosyltransferase
IPR027791 Galactosyltransferase, C-terminal
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF02709
PRINTS PR02050
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R087
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 218271
UniGene Mm.139825
RefSeq XP_006517279
MGI ID
MGI Symbol B4galt7
OMIM
CCDS
HPRD
IMGT
EMBL BC027195 BC055703
GenPept AAH27195 AAH55703

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca