InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lhx4

Summary

InnateDB Protein

IDBP-199900.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lhx4

Protein Name

LIM homeobox protein 4

Synonyms

A330062J17Rik; Gsh-4; Gsh4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000027740

InnateDB Gene

IDBG-199898 (Lhx4)

Protein Structure

UniProt Annotation

Function

May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.

Disease Associations

Tissue Specificity

Transient expression in ventrolateral regions of the developing neural tube and hindbrain.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0001890	placenta development
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0008045	motor neuron axon guidance
GO:0009887	organ morphogenesis
GO:0021526	medial motor column neuron differentiation
GO:0043066	negative regulation of apoptotic process