InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Zcchc8

Summary

InnateDB Protein

IDBP-199903.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Zcchc8

Protein Name

zinc finger, CCHC domain containing 8

Synonyms

5730565F05Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031376

InnateDB Gene

IDBG-199901 (Zcchc8)

Protein Structure

UniProt Annotation

Function

May be involved in pre-mRNA splicing. {ECO:0000250}.

Subcellular Localization

Nucleus, nucleoplasm {ECO:0000250}. Note=Excluded from nucleolus. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006397	mRNA processing
GO:0008150	biological_process
GO:0008380	RNA splicing

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0071013	catalytic step 2 spliceosome

Protein Structure and Domains

PDB ID

MGI:1917900

InterPro

IPR001878 Zinc finger, CCHC-type
IPR006568 PSP, proline-rich

PFAM

PF00098
PF04046

PRINTS

PIRSF

SMART

SM00343
SM00581

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CYA6

PhosphoSite

PhosphoSite-Q9CYA6

TrEMBL

Q3TKH5

UniProt Splice Variant

Entrez Gene

70650

UniGene

Mm.395291

RefSeq

NP_081770

MGI ID

MGI Symbol

Zcchc8

OMIM

CCDS

HPRD

IMGT

EMBL

AK017857 AK033469 AK156770 AK166990 AK167126 AK167736 BC013555

GenPept

AAH13555 BAB30977 BAC28304 BAE33847 BAE39170 BAE39274 BAE39776