InnateDB Protein
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IDBP-200104.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tor1aip1
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Protein Name
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torsin A interacting protein 1
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000027738
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InnateDB Gene
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IDBG-200102 (Tor1aip1)
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Protein Structure
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Function |
Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina. {ECO:0000269PubMed:20457914}.
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Subcellular Localization |
Nucleus inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed in the spinal cord and liver (at protein level). {ECO:0000269PubMed:16364897}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
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Protein-Protein |
13
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
19 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:3582693
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InterPro |
IPR008662
Lamina-associated polypeptide 1C
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PFAM |
PF05609
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q921T2
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PhosphoSite |
PhosphoSite-Q921T2
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
208263
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UniGene |
Mm.211654
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RefSeq |
NP_659040
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MGI ID |
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MGI Symbol |
Tor1aip1
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OMIM |
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CCDS |
CCDS15387
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HPRD |
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IMGT |
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EMBL |
AB251963
AC159964
AK152751
BC010841
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GenPept |
AAH10841
BAE31466
BAE94915
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