InnateDB Protein
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IDBP-200326.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Acer3
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Protein Name
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alkaline ceramidase 3
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Synonyms
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1110057L18Rik; 5430429L08Rik; AV015045; Phca;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000033020
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InnateDB Gene
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IDBG-200324 (Acer3)
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Protein Structure
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Function |
Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (By similarity). {ECO:0000250}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0016811
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hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
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GO:0070774
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phytoceramidase activity
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Biological Process |
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Cellular Component |
GO:0016021
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integral component of membrane
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GO:0030173
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integral component of Golgi membrane
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GO:0030176
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integral component of endoplasmic reticulum membrane
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PDB ID |
MGI:1913440
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InterPro |
IPR008901
Ceramidase
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PFAM |
PF05875
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9D099
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PhosphoSite |
PhosphoSite-
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TrEMBL |
D3YTU8
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UniProt Splice Variant |
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Entrez Gene |
66190
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UniGene |
Mm.399775
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RefSeq |
NP_079684
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MGI ID |
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MGI Symbol |
Acer3
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OMIM |
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CCDS |
CCDS21468
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HPRD |
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IMGT |
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EMBL |
AC111084
AC119880
AK004287
AK011668
AK017361
AK080977
AK150629
AK162403
CH466531
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GenPept |
BAB23250
BAB27768
BAB30708
BAC38101
BAE29719
BAE36897
EDL16340
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