InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc25a20

Summary

InnateDB Protein

IDBP-200414.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc25a20

Protein Name

solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20

Synonyms

1110007P09Rik; C78826; Cact; mCAC;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035222

InnateDB Gene

IDBG-200412 (Slc25a20)

Protein Structure

UniProt Annotation

Function

Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Widely expressed, with highest levels in the liver, intermediate levels in heart, testis and kidney and low levels in brain, including cortex, cerebellum, hippocampus and hypothalamus. {ECO:0000269PubMed:19287344}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0006810

transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1928738

InterPro

IPR018108 Mitochondrial substrate/solute carrier
IPR023395 Mitochondrial carrier domain

PFAM

PF00153

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9Z2Z6

PhosphoSite

PhosphoSite-Q9Z2Z6

TrEMBL

UniProt Splice Variant

Entrez Gene

57279

UniGene

Mm.395974

RefSeq

NP_065266

MGI ID

MGI Symbol

Slc25a20

OMIM

CCDS

CCDS23535

HPRD

IMGT

EMBL

AB017112 AK075624 AK152436 BC029733

GenPept

AAH29733 BAA74768 BAC35865 BAE31218