InnateDB Protein
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IDBP-200423.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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2210018M11Rik
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Protein Name
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RIKEN cDNA 2210018M11 gene
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000038216
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InnateDB Gene
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IDBG-200421 (2210018M11Rik)
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Protein Structure
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Function |
Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2 (By similarity). As part of a H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors (By similarity). {ECO:0000250}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:14651845}. Note=Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
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Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
10 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1924203
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InterPro |
IPR005491
EMSY N-terminal
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PFAM |
PF03735
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8BMB0
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PhosphoSite |
PhosphoSite-Q8BMB0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
233545
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UniGene |
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RefSeq |
NP_758484
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MGI ID |
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MGI Symbol |
2210018M11Rik
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OMIM |
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CCDS |
CCDS40028
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HPRD |
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IMGT |
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EMBL |
AK032985
BC020109
BC039956
BC089304
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GenPept |
AAH20109
AAH89304
BAC28113
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