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InnateDB Protein
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IDBP-200531.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Exoc8
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Protein Name
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exocyst complex component 8
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Synonyms
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AI414418; EXO84; Exo84p; R74783; SEC84;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000095915
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InnateDB Gene
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IDBG-200529 (Exoc8)
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Protein Structure
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| Function |
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. {ECO:0000250}.
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| Subcellular Localization |
Cytoplasm. Cell projection, growth cone {ECO:0000250}. Note=Redistributes to growing neurites and growth cones during cell differentiation. Binds lipids with phosphatidylinositol 3,4,5-trisphosphate groups (By similarity). {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
2
[view]
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| Protein-Protein |
2
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
26 [view]
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
MGI:2142527
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| InterPro |
IPR001849
Pleckstrin homology domain
IPR016159
Cullin repeat-like-containing domain
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| PFAM |
PF00169
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| PRINTS |
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| PIRSF |
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| SMART |
SM00233
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q6PGF7
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| PhosphoSite |
PhosphoSite-Q6PGF7
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
102058
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| UniGene |
Mm.392449
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| RefSeq |
NP_932771
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| MGI ID |
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| MGI Symbol |
Exoc8
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| OMIM |
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| CCDS |
CCDS22777
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| HPRD |
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| IMGT |
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| EMBL |
BC057052
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| GenPept |
AAH57052
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Version 5.4