Version 5.4
Mus musculus Protein: Atrip
Summary
InnateDB Protein IDBP-201155.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atrip
Protein Name ATR interacting protein
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000044831
InnateDB Gene IDBG-201153 (Atrip)
Protein Structure
UniProt Annotation
Function Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Note=Redistributes to discrete nuclear foci upon DNA damage. Interacts with CEP164 (via N-terminus) (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006281 DNA repair
Cellular Component
GO:0005634 nucleus
GO:0015630 microtubule cytoskeleton
Protein Structure and Domains
PDB ID MGI:1925349
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BMG1
PhosphoSite PhosphoSite-Q8BMG1
TrEMBL Q9CRN1
UniProt Splice Variant
Entrez Gene 235610
UniGene Mm.467431
RefSeq NP_766362
MGI ID
MGI Symbol Atrip
OMIM
CCDS CCDS23545
HPRD
IMGT
EMBL AC174646 AK020102 AK031257
GenPept BAB31994 BAC27324

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca