Version 5.4
Mus musculus Protein: Plekhm2
Summary
InnateDB Protein IDBP-202274.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plekhm2
Protein Name pleckstrin homology domain containing, family M (with RUN domain) member 2
Synonyms 2310034J19Rik; AI854247; mKIAA0842;
Species Mus musculus
Ensembl Protein ENSMUSP00000081221
InnateDB Gene IDBG-202272 (Plekhm2)
Protein Structure
UniProt Annotation
Function May play a role in the regulation of conventional kinesin activity. Required for maintenance of the Golgi apparatus organization. May play a role in membrane tubulation (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019894 kinesin binding
Biological Process
GO:0007030 Golgi organization
Cellular Component
Protein Structure and Domains
PDB ID MGI:1916832
InterPro IPR001849 Pleckstrin homology domain
IPR004012 RUN
PFAM PF00169
PF02759
PRINTS
PIRSF
SMART SM00233
SM00593
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q80TQ5
TrEMBL Z4YJW6
UniProt Splice Variant
Entrez Gene 69582
UniGene Mm.33220
RefSeq NP_001028322
MGI ID
MGI Symbol Plekhm2
OMIM
CCDS CCDS51348
HPRD
IMGT
EMBL AL670446
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca