InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Aldoc

Summary

InnateDB Protein

IDBP-202684.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Aldoc

Protein Name

aldolase C, fructose-bisphosphate

Synonyms

AI847350; Aldo3; AU040929; Scrg2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000017534

InnateDB Gene

IDBG-202678 (Aldoc)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed exclusively in Purkinje cells in bands running from anterior to posterior across most of the cerebellum. Expressed at higher levels in the brains of BSE- infected animals. {ECO:0000269PubMed:10719228, ECO:0000269PubMed:7925012}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004332	fructose-bisphosphate aldolase activity
GO:0008092	cytoskeletal protein binding

Biological Process

GO:0001666	response to hypoxia
GO:0006096	glycolytic process
GO:0006915	apoptotic process
GO:0007568	aging
GO:0010243	response to organonitrogen compound
GO:0014070	response to organic cyclic compound
GO:0030388	fructose 1,6-bisphosphate metabolic process
GO:0031100	organ regeneration
GO:0051289	protein homotetramerization
GO:0051290	protein heterotetramerization