InnateDB Protein
|
IDBP-204348.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Usp50
|
Protein Name
|
ubiquitin specific peptidase 50
|
Synonyms
|
1700086G18Rik; 4930511O11Rik;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000028842
|
InnateDB Gene
|
IDBG-204346 (Usp50)
|
Protein Structure
|
|
Function |
May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly- ubiquitin precursors as well as that of ubiquitinated proteins (By similarity). {ECO:0000250}.
|
Subcellular Localization |
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
23 [view]
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0008234
|
cysteine-type peptidase activity
|
GO:0036459
|
ubiquitinyl hydrolase activity
|
|
Biological Process |
GO:0006511
|
ubiquitin-dependent protein catabolic process
|
|
Cellular Component |
|
PDB ID |
MGI:1922333
|
InterPro |
IPR001394
Peptidase C19, ubiquitin carboxyl-terminal hydrolase
IPR028889
Ubiquitin carboxyl-terminal hydrolase-like domain
|
PFAM |
PF00443
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q6P8X6
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
75083
|
UniGene |
Mm.389373
|
RefSeq |
NP_083439
|
MGI ID |
|
MGI Symbol |
Usp50
|
OMIM |
|
CCDS |
CCDS16688
|
HPRD |
|
IMGT |
|
EMBL |
AK007018
AK015766
BC061020
|
GenPept |
AAH61020
BAB24831
BAB29966
|
|
|