Version 5.4
Mus musculus Protein: Casz1
Summary
InnateDB Protein IDBP-204812.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Casz1
Protein Name castor homolog 1, zinc finger (Drosophila)
Synonyms 2410019P08Rik; AV096627; BC040081; Cst; D4Ertd432e;
Species Mus musculus
Ensembl Protein ENSMUSP00000092035
InnateDB Gene IDBG-204810 (Casz1)
Protein Structure
UniProt Annotation
Function Transcription factor involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in the brain stem and the thalamencephalon. {ECO:0000269PubMed:12351199, ECO:0000269PubMed:16631614}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1196251
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CWL2
PhosphoSite PhosphoSite-Q9CWL2
TrEMBL B1AS47
UniProt Splice Variant
Entrez Gene 69743
UniGene Mm.393949
RefSeq NP_081471
MGI ID
MGI Symbol Casz1
OMIM
CCDS CCDS38973
HPRD
IMGT
EMBL AK010559 AK173341 AL607145 AL611967
GenPept BAB27027 BAD32619 CAM18127

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca