Mus musculus Protein: Pop7
Summary
InnateDB Protein IDBP-205023.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pop7
Protein Name processing of precursor 7, ribonuclease P family, (S. cerevisiae)
Synonyms 0610037N12Rik; AI852017; Rpp20;
Species Mus musculus
Ensembl Protein ENSMUSP00000031728
InnateDB Gene IDBG-205021 (Pop7)
Protein Structure
UniProt Annotation
Function Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cytoplasmic granule {ECO:0000250}. Note=Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004526 ribonuclease P activity
Biological Process
GO:0008033 tRNA processing
GO:0008150 biological_process
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1921347
InterPro IPR002775 DNA/RNA-binding protein Alba-like
IPR014612 Ribonuclease P/MRP, subunit p20
PFAM PF01918
PRINTS
PIRSF PIRSF036572
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9DCH2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 74097
UniGene
RefSeq
MGI ID
MGI Symbol Pop7
OMIM
CCDS CCDS19768
HPRD
IMGT
EMBL AF312033 AK002782 AK158620 AK162268 BC010780
GenPept AAH10780 AAK28826 BAB22355 BAE34584 BAE36826