Mus musculus Protein: Pcolce | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-205229.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Pcolce | ||||||||||
Protein Name | procollagen C-endopeptidase enhancer protein | ||||||||||
Synonyms | Astt-2; Astt2; P14; PCPE-1; | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Protein | ENSMUSP00000031731 | ||||||||||
InnateDB Gene | IDBG-205227 (Pcolce) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity. | ||||||||||
Subcellular Localization | Secreted. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | Expressed in interstitial connective tissues like tendons, calvaria, skin and at a lower level in heart and skeletal muscle. {ECO:0000269PubMed:2256940}. | ||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | MGI:105099 | ||||||||||
InterPro |
IPR000859
CUB domain IPR001134 Netrin domain IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold IPR018933 Netrin module, non-TIMP type |
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PFAM |
PF00431
PF01759 |
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PRINTS | |||||||||||
PIRSF | |||||||||||
SMART |
SM00042
SM00643 |
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TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q61398 | ||||||||||
PhosphoSite | PhosphoSite-Q61398 | ||||||||||
TrEMBL | Q3UIP2 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 18542 | ||||||||||
UniGene | Mm.262345 | ||||||||||
RefSeq | NP_032814 | ||||||||||
MGI ID | |||||||||||
MGI Symbol | Pcolce | ||||||||||
OMIM | |||||||||||
CCDS | CCDS39334 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AB008548 AC124730 AK142615 AK146829 CH466529 X57337 | ||||||||||
GenPept | BAA23280 BAE25130 BAE27464 CAA40612 EDL19252 | ||||||||||