InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mepce

Summary

InnateDB Protein

IDBP-205475.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mepce

Protein Name

methylphosphate capping enzyme

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000031740

InnateDB Gene

IDBG-205473 (Mepce)

Protein Structure

UniProt Annotation

Function

S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 158 interaction(s) predicted by orthology.

Predicted by orthology
Total	158 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008168	methyltransferase activity
GO:0008173	RNA methyltransferase activity
GO:0008276	protein methyltransferase activity
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001510	RNA methylation
GO:0006479	protein methylation
GO:0016073	snRNA metabolic process
GO:0035562	negative regulation of chromatin binding
GO:0040031	snRNA modification
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle