Version 5.4
Mus musculus Protein: Hhatl
Summary
InnateDB Protein IDBP-205631.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hhatl
Protein Name hedgehog acyltransferase-like
Synonyms 1110011D13Rik; Gup1;
Species Mus musculus
Ensembl Protein ENSMUSP00000035110
InnateDB Gene IDBG-205629 (Hhatl)
Protein Structure
UniProt Annotation
Function Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN. {ECO:0000269PubMed:18081866}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:18081866}; Multi-pass membrane protein {ECO:0000269PubMed:18081866}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0060262 negative regulation of N-terminal protein palmitoylation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID MGI:1922020
InterPro IPR004299 Membrane bound O-acyl transferase, MBOAT
PFAM PF03062
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D1G3
PhosphoSite PhosphoSite-Q9D1G3
TrEMBL
UniProt Splice Variant
Entrez Gene 74770
UniGene Mm.44195
RefSeq NP_083371
MGI ID
MGI Symbol Hhatl
OMIM
CCDS CCDS23638
HPRD
IMGT
EMBL AK003605 AK157924 BC024464
GenPept AAH24464 BAB22885 BAE34266

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca