Version 5.4
Mus musculus Protein: Ttl
Summary
InnateDB Protein IDBP-205698.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ttl
Protein Name tubulin tyrosine ligase
Synonyms 2410003M22Rik; 2700049H19Rik; AI848570;
Species Mus musculus
Ensembl Protein ENSMUSP00000046883
InnateDB Gene IDBG-205696 (Ttl)
Protein Structure
UniProt Annotation
Function Catalyzes the post-translational addition of a tyrosine to the C-terminal end of detyrosinated alpha-tubulin.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004835 tubulin-tyrosine ligase activity
GO:0005524 ATP binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0006464 cellular protein modification process
GO:0030516 regulation of axon extension
Cellular Component
GO:0005874 microtubule
Protein Structure and Domains
PDB ID MGI:1916987
InterPro IPR004344 Tubulin-tyrosine ligase/Tubulin polyglutamylase
PFAM PF03133
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P38585
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 69737
UniGene Mm.33909
RefSeq NP_081468
MGI ID
MGI Symbol Ttl
OMIM
CCDS CCDS16719
HPRD
IMGT
EMBL BC018513 BC024414
GenPept AAH18513 AAH24414

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca