Version 5.4
Homo sapiens Protein: ELN
Summary
InnateDB Protein IDBP-20573.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELN
Protein Name elastin
Synonyms SVAS; WBS; WS;
Species Homo sapiens
Ensembl Protein ENSP00000351807
InnateDB Gene IDBG-20555 (ELN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005201 extracellular matrix structural constituent
GO:0005515 protein binding
GO:0030023 extracellular matrix constituent conferring elasticity
GO:0050840 extracellular matrix binding
Biological Process
GO:0001974 blood vessel remodeling
GO:0007519 skeletal muscle tissue development
GO:0030198 extracellular matrix organization
GO:0030833 regulation of actin filament polymerization
GO:0043149 stress fiber assembly
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005739 mitochondrion
GO:0071953 elastic fiber
Protein Structure and Domains
PDB ID
InterPro IPR003979 Tropoelastin
PFAM
PRINTS PR01500
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9UMK5
UniProt Splice Variant
Entrez Gene 2006
UniGene Hs.647061
RefSeq NP_001265868
HUGO HGNC:3327
OMIM 130160
CCDS CCDS75616
HPRD 00556
IMGT
EMBL AC005056 J04821
GenPept AAA52379

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca