Version 5.4
Homo sapiens Protein: CAMTA2
Summary
InnateDB Protein IDBP-20589.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAMTA2
Protein Name calmodulin binding transcription activator 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000354828
InnateDB Gene IDBG-20579 (CAMTA2)
Protein Structure
UniProt Annotation
Function Transcription activator. May act as tumor suppressor. {ECO:0000269PubMed:11925432}.
Subcellular Localization Nucleus {ECO:0000305PubMed:11925432}.
Disease Associations
Tissue Specificity Detected in brain. Expressed at constant levels throughout the cell cycle in neuroblastoma cell lines. {ECO:0000269PubMed:11925432, ECO:0000269PubMed:15138581}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0008134 transcription factor binding
GO:0042826 histone deacetylase binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0014898 cardiac muscle hypertrophy in response to stress
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000048 IQ motif, EF-hand binding site
IPR002909 IPT domain
IPR005559 CG-1 DNA-binding domain
IPR014756 Immunoglobulin E-set
IPR020683 Ankyrin repeat-containing domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00612
PF01833
PF03859
PF11929
PF12796
PRINTS
PIRSF
SMART SM00015
SM00429
SM01076
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94983
PhosphoSite PhosphoSite-O94983
TrEMBL Q8N5H1
UniProt Splice Variant
Entrez Gene 23125
UniGene Hs.712854
RefSeq NP_001164639
HUGO HGNC:18807
OMIM 611508
CCDS CCDS54071
HPRD 13002
IMGT
EMBL AB020716 AC004771 AL831849 AL833974 BC010050 BC016163 BC032381 BC136534 BC142606 BC144232 CH471108
GenPept AAH10050 AAH16163 AAH32381 AAI36535 AAI44233 BAA74932 CAD38553 CAD38818 EAW90372 EAW90373

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca