Version 5.4
Mus musculus Protein: Tnfrsf9
Summary
InnateDB Protein IDBP-205906.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Tnfrsf9
Protein Name tumor necrosis factor receptor superfamily, member 9
Synonyms 4-1BB; A930040I11Rik; AA408498; AI325004; Cd137; CDw137; ILA; Ly63;
Species Mus musculus
Ensembl Protein ENSMUSP00000059684
InnateDB Gene IDBG-205902 (Tnfrsf9)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0019955 cytokine binding
Biological Process
GO:0042127 regulation of cell proliferation
GO:0045087 innate immune response (InnateDB)
GO:0070207 protein homotrimerization
GO:2001180 negative regulation of interleukin-10 secretion
GO:2001183 negative regulation of interleukin-12 secretion
Cellular Component
GO:0005615 extracellular space
GO:0009897 external side of plasma membrane
Protein Structure and Domains
PDB ID MGI:1101059
InterPro IPR001368 TNFR/NGFR cysteine-rich region
PFAM PF00020
PRINTS
PIRSF
SMART SM00208
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8R037
UniProt Splice Variant
Entrez Gene 21942
UniGene Mm.416252
RefSeq
MGI ID
MGI Symbol Tnfrsf9
OMIM
CCDS CCDS38980
HPRD
IMGT
EMBL AL607084 AL607143 BC028507 DQ832279
GenPept AAH28507 ABI30213

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca