InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Akip1

Summary

InnateDB Protein

IDBP-206221.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Akip1

Protein Name

RIKEN cDNA D930014E17 gene

Synonyms

BCA3; C11orf17; D7H11orf17; D930014E17Rik; ICRFP703B1614Q5.6; ORF27;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000033335

InnateDB Gene

IDBG-206219 (Akip1)

Protein Structure

UniProt Annotation

Function

Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}. Note=Locates to punctate spots. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0034446

substrate adhesion-dependent cell spreading

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:3041226

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9JJR5

PhosphoSite

PhosphoSite-Q9JJR5

TrEMBL

UniProt Splice Variant

Entrez Gene

57373

UniGene

RefSeq

NP_065641

MGI ID

MGI Symbol

Akip1

OMIM

CCDS

CCDS21736

HPRD

IMGT

EMBL

AJ400878 AK086219 AK163012

GenPept

BAC39632 BAE37154 CAB92298