InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Avp

Summary

InnateDB Protein

IDBP-206578.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Avp

Protein Name

arginine vasopressin

Synonyms

Vp; Vsp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000035551

InnateDB Gene

IDBG-206576 (Avp)

Protein Structure

UniProt Annotation

Function

Neurophysin 2 specifically binds vasopressin.Vasopressin has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels.

Subcellular Localization

Secreted.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004871	signal transducer activity
GO:0005185	neurohypophyseal hormone activity
GO:0005515	protein binding
GO:0031894	V1A vasopressin receptor binding
GO:0031895	V1B vasopressin receptor binding
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Biological Process

GO:0002125	maternal aggressive behavior
GO:0003084	positive regulation of systemic arterial blood pressure
GO:0006468	protein phosphorylation
GO:0007165	signal transduction
GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0007621	negative regulation of female receptivity
GO:0007625	grooming behavior
GO:0007626	locomotory behavior
GO:0008284	positive regulation of cell proliferation
GO:0010628	positive regulation of gene expression
GO:0014049	positive regulation of glutamate secretion
GO:0014070	response to organic cyclic compound
GO:0030307	positive regulation of cell growth
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0031394	positive regulation of prostaglandin biosynthetic process
GO:0032849	positive regulation of cellular pH reduction
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0033574	response to testosterone
GO:0035094	response to nicotine
GO:0035176	social behavior
GO:0035813	regulation of renal sodium excretion
GO:0042310	vasoconstriction
GO:0042538	hyperosmotic salinity response
GO:0042711	maternal behavior
GO:0043066	negative regulation of apoptotic process
GO:0043084	penile erection
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045087	innate immune response (InnateDB)
GO:0045471	response to ethanol
GO:0045907	positive regulation of vasoconstriction
GO:0050891	multicellular organismal water homeostasis
GO:0051970	negative regulation of transmission of nerve impulse
GO:0070371	ERK1 and ERK2 cascade
GO:0070528	protein kinase C signaling
GO:0090201	negative regulation of release of cytochrome c from mitochondria