Version 5.4
| Mus musculus Protein: Acbd3 | |||||||||||
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| Summary | |||||||||||
| InnateDB Protein | IDBP-207266.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Acbd3 | ||||||||||
| Protein Name | acyl-Coenzyme A binding domain containing 3 | ||||||||||
| Synonyms | |||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Protein | ENSMUSP00000027780 | ||||||||||
| InnateDB Gene | IDBG-207264 (Acbd3) | ||||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||||
| Function | Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi (By similarity). Involved in hormone-induced steroid biosynthesis in testicular Leydig cells. {ECO:0000250, ECO:0000269PubMed:12711385}. | ||||||||||
| Subcellular Localization | Golgi apparatus membrane {ECO:0000269PubMed:12711385}; Peripheral membrane protein {ECO:0000269PubMed:12711385}; Cytoplasmic side {ECO:0000269PubMed:12711385}. Mitochondrion {ECO:0000269PubMed:12711385}. Note=Also mitochondrial (via its interaction with PBR). | ||||||||||
| Disease Associations | |||||||||||
| Tissue Specificity | Expressed in brain (hippocampus, olfactory bulb, neuronal and glial cells of the cortex), eye, submaxillary gland, testis (interstitial and tubular compartments), ovary (granulosa cells, theca cells at late stages and primary follicles), adrenal gland (fasciculata and glomerulosa cells), heart, liver, and steroidogenic cell lines. {ECO:0000269PubMed:11731621}. | ||||||||||
| Comments | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||||
| PDB ID | MGI:2181074 | ||||||||||
| InterPro |
IPR000582
Acyl-CoA-binding protein, ACBP IPR009038 GOLD |
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| PFAM |
PF00887
PF01105 PF13897 |
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| PRINTS |
PR00689
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| PIRSF | |||||||||||
| SMART | |||||||||||
| TIGRFAMs | |||||||||||
| Post-translational Modifications | |||||||||||
| Modification | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q8BMP6 | ||||||||||
| PhosphoSite | PhosphoSite-Q8BMP6 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 170760 | ||||||||||
| UniGene | Mm.472382 | ||||||||||
| RefSeq | NP_573488 | ||||||||||
| MGI ID | |||||||||||
| MGI Symbol | Acbd3 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS15572 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | AF022770 AF501319 AK030371 | ||||||||||
| GenPept | AAB71197 AAM22185 BAC26928 | ||||||||||