Version 5.4
Mus musculus Protein: Chgb
Summary
InnateDB Protein IDBP-207467.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Chgb
Protein Name chromogranin B
Synonyms Scg-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000028826
InnateDB Gene IDBG-207465 (Chgb)
Protein Structure
UniProt Annotation
Function Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.
Subcellular Localization Secreted. Note=Neuroendocrine and endocrine secretory granules.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005576 extracellular region
GO:0030141 secretory granule
Protein Structure and Domains
PDB ID MGI:88395
InterPro IPR001819 Chromogranin A/B
IPR001990 Chromogranin/secretogranin
PFAM PF01271
PRINTS PR00659
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P16014
PhosphoSite PhosphoSite-P16014
TrEMBL Q3TY66
UniProt Splice Variant
Entrez Gene 12653
UniGene Mm.255241
RefSeq NP_031720
MGI ID
MGI Symbol Chgb
OMIM
CCDS CCDS16777
HPRD
IMGT
EMBL AK158857 BC014736 CH466519 X51429 X53028
GenPept AAH14736 BAE34697 CAA35792 CAA37199 EDL28358

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca