Version 5.4
Mus musculus Protein: Srp9
Summary
InnateDB Protein IDBP-207661.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Srp9
Protein Name signal recognition particle 9
Synonyms 9kDa;
Species Mus musculus
Ensembl Protein ENSMUSP00000027792
InnateDB Gene IDBG-207659 (Srp9)
Protein Structure
UniProt Annotation
Function Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008312 7S RNA binding
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0045900 negative regulation of translational elongation
Cellular Component
GO:0005786 signal recognition particle, endoplasmic reticulum targeting
GO:0048500 signal recognition particle
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1350930
InterPro IPR008832 Signal recognition particle, SRP9 subunit
IPR009018 Signal recognition particle, SRP9/SRP14 subunit
PFAM
PRINTS
PIRSF PIRSF017029
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P49962
PhosphoSite PhosphoSite-P49962
TrEMBL Q5EAT0
UniProt Splice Variant
Entrez Gene 27058
UniGene Mm.482409
RefSeq NP_036188
MGI ID 1914
MGI Symbol Srp9
OMIM
CCDS CCDS35812
HPRD
IMGT
EMBL AK011720 AK020583 AK020620 AK051208 AK169314 BC039648 BC090254 CH466555 X78304
GenPept AAH39648 AAH90254 BAB27800 BAB32138 BAB32151 BAC34557 BAE41069 CAA55114 EDL13112

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca