InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gprc5b

Summary

InnateDB Protein

IDBP-207882.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gprc5b

Protein Name

G protein-coupled receptor, family C, group 5, member B

Synonyms

AW125761; Raig2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000008878

InnateDB Gene

IDBG-207880 (Gprc5b)

Protein Structure

UniProt Annotation

Function

Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways (By similarity). {ECO:0000250}.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0019901	protein kinase binding
GO:0030295	protein kinase activator activity

Biological Process

GO:0001934	positive regulation of protein phosphorylation
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007626	locomotory behavior
GO:0010976	positive regulation of neuron projection development
GO:0042593	glucose homeostasis
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045666	positive regulation of neuron differentiation
GO:0045860	positive regulation of protein kinase activity
GO:0050729	positive regulation of inflammatory response
GO:0060907	positive regulation of macrophage cytokine production
GO:0061098	positive regulation of protein tyrosine kinase activity
GO:0090263	positive regulation of canonical Wnt signaling pathway

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0045121	membrane raft
GO:0070062	extracellular vesicular exosome