Version 5.4
Mus musculus Protein: Acsm5
Summary
InnateDB Protein IDBP-207975.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acsm5
Protein Name acyl-CoA synthetase medium-chain family member 5
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000063416
InnateDB Gene IDBG-207973 (Acsm5)
Protein Structure
UniProt Annotation
Function Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4- unsaturated acids (in vitro) (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion matrix {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0047760 butyrate-CoA ligase activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005759 mitochondrial matrix
Protein Structure and Domains
PDB ID MGI:2444086
InterPro IPR000873 AMP-dependent synthetase/ligase
PFAM PF00501
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BGA8
PhosphoSite PhosphoSite-Q8BGA8
TrEMBL
UniProt Splice Variant
Entrez Gene 272428
UniGene Mm.185183
RefSeq NP_848873
MGI ID
MGI Symbol Acsm5
OMIM
CCDS CCDS40106
HPRD
IMGT
EMBL AK040650 AK050132 AK050219 AK050288 AK050458 AK080219 AK149591 BC095985
GenPept AAH95985 BAC30656 BAC34084 BAC34130 BAC34167 BAC34268 BAC37850 BAE28980

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca