InnateDB Protein
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IDBP-208346.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Crym
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Protein Name
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crystallin, mu
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000033198
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InnateDB Gene
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IDBG-208344 (Crym)
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Protein Structure
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Function |
Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:102675
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InterPro |
IPR003462
Ornithine cyclodeaminase/mu-crystallin
IPR006151
Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
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PFAM |
PF02423
PF01488
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PRINTS |
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PIRSF |
PIRSF001439
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O54983
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PhosphoSite |
PhosphoSite-O54983
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TrEMBL |
Q3UPX0
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UniProt Splice Variant |
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Entrez Gene |
12971
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UniGene |
Mm.9114
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RefSeq |
NP_057878
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MGI ID |
4BVA
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MGI Symbol |
Crym
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OMIM |
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CCDS |
CCDS21794
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HPRD |
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IMGT |
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EMBL |
AF039391
AK138422
AK143116
AK163781
BC045159
CH466531
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GenPept |
AAB94770
AAH45159
BAE23654
BAE25274
BAE37489
EDL17205
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