Version 5.4
Mus musculus Protein: Rbbp9
Summary
InnateDB Protein IDBP-208556.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rbbp9
Protein Name retinoblastoma binding protein 9
Synonyms Bog;
Species Mus musculus
Ensembl Protein ENSMUSP00000028915
InnateDB Gene IDBG-208554 (Rbbp9)
Protein Structure
UniProt Annotation
Function May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:1347074
InterPro IPR010662 Protein of unknown function DUF1234, hydrolase
IPR029058 Alpha/Beta hydrolase fold
PFAM PF06821
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O88851
PhosphoSite PhosphoSite-O88851
TrEMBL A2AN96
UniProt Splice Variant
Entrez Gene 26450
UniGene Mm.440564
RefSeq NP_056569
MGI ID
MGI Symbol Rbbp9
OMIM
CCDS CCDS16821
HPRD
IMGT
EMBL AF039563 AK017606 BC011107 BC147814 BC147815 CH466519
GenPept AAC63497 AAH11107 AAI47815 AAI47816 EDL28466

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca