Version 5.4
Mus musculus Protein: Otoa
Summary
InnateDB Protein IDBP-208702.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Otoa
Protein Name otoancorin
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000044177
InnateDB Gene IDBG-208700 (Otoa)
Protein Structure
UniProt Annotation
Function May act as an adhesion molecule. {ECO:0000269PubMed:11972037}.
Subcellular Localization Apical cell membrane {ECO:0000305PubMed:11972037}; Lipid-anchor, GPI-anchor {ECO:0000305PubMed:11972037}; Extracellular side {ECO:0000305PubMed:11972037}. Secreted, extracellular space, extracellular matrix {ECO:0000305PubMed:11972037}. Note=At the interface between the apical surface of the epithelia and the overlying acellular gel of the tectorial and otoconial membranes.
Disease Associations
Tissue Specificity Expressed in the inner ear and vestibule. {ECO:0000269PubMed:11972037}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007160 cell-matrix adhesion
GO:0007605 sensory perception of sound
GO:0019226 transmission of nerve impulse
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0016324 apical plasma membrane
GO:0031225 anchored component of membrane
Protein Structure and Domains
PDB ID MGI:2149209
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8K561
PhosphoSite PhosphoSite-Q8K561
TrEMBL E9PVT3
UniProt Splice Variant
Entrez Gene 246190
UniGene
RefSeq NP_647471
MGI ID
MGI Symbol Otoa
OMIM
CCDS CCDS40114
HPRD
IMGT
EMBL AC140782 AY055122
GenPept AAL27794

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca