Version 5.4
Homo sapiens Protein: FUT5
Summary
InnateDB Protein IDBP-20924.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FUT5
Protein Name fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
Synonyms FUC-TV;
Species Homo sapiens
Ensembl Protein ENSP00000252675
InnateDB Gene IDBG-20922 (FUT5)
Protein Structure
UniProt Annotation
Function May catalyze alpha-1,3 glycosidic linkages involved in the expression of VIM-2, Lewis X/SSEA-1 and sialyl Lewis X antigens.
Subcellular Localization Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Disease Associations
Tissue Specificity Liver, colon and testis and trace amounts in T-cells and brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008417 fucosyltransferase activity
GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity
GO:0046920 alpha-(1->3)-fucosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006486 protein glycosylation
GO:0036065 fucosylation
GO:0042355 L-fucose catabolic process
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
Protein Structure and Domains
PDB ID
InterPro IPR001503 Glycosyl transferase, family 10
PFAM PF00852
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q11128
PhosphoSite PhosphoSite-Q11128
TrEMBL K7ENC0
UniProt Splice Variant
Entrez Gene 2527
UniGene Hs.631843
RefSeq
HUGO HGNC:4016
OMIM 136835
CCDS CCDS12154
HPRD 00650
IMGT
EMBL AC024592 AC104532 AK291087 BC140905 CH471139 M81485 U27329 U27330
GenPept AAA98117 AAC50188 AAC50189 AAI40906 BAF83776 EAW69134

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca