InnateDB Protein
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IDBP-209297.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cst7
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Protein Name
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cystatin F (leukocystatin)
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Synonyms
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Cmap;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000086606
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InnateDB Gene
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IDBG-209295 (Cst7)
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Protein Structure
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|
Function |
Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.
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Subcellular Localization |
Secreted {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
1 [view]
|
|
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Molecular Function |
Accession |
GO Term |
GO:0004869
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cysteine-type endopeptidase inhibitor activity
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GO:0005515
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protein binding
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|
Biological Process |
GO:0010951
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negative regulation of endopeptidase activity
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|
Cellular Component |
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PDB ID |
MGI:1298217
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InterPro |
IPR000010
Proteinase inhibitor I25, cystatin
|
PFAM |
PF00031
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PRINTS |
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PIRSF |
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SMART |
SM00043
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TIGRFAMs |
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Modification |
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SwissProt |
O89098
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PhosphoSite |
PhosphoSite-
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TrEMBL |
Q9QWL5
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UniProt Splice Variant |
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Entrez Gene |
13011
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UniGene |
|
RefSeq |
NP_034107
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MGI ID |
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MGI Symbol |
Cst7
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OMIM |
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CCDS |
CCDS16857
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HPRD |
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IMGT |
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EMBL |
AB015224
AF031825
AF031826
AK004420
AK170583
BC117047
BC117049
CH466519
|
GenPept |
AAC40139
AAC40140
AAI17048
AAI17050
BAA34940
BAB23298
BAE41893
EDL28568
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