InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cd19

Summary

InnateDB Protein

IDBP-209477.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cd19

Protein Name

CD19 antigen

Synonyms

AW495831;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032968

InnateDB Gene

IDBG-209475 (Cd19)

Protein Structure

UniProt Annotation

Function

Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	4 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0050853

B cell receptor signaling pathway

Cellular Component

GO:0009897	external side of plasma membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:88319

InterPro

IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain

PFAM

PRINTS

PIRSF

SMART

SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P25918

PhosphoSite

PhosphoSite-P25918

TrEMBL

Q3TQG5

UniProt Splice Variant

Entrez Gene

12478

UniGene

Mm.4360

RefSeq

NP_033974

MGI ID

MGI Symbol

Cd19

OMIM

CCDS

CCDS21828

HPRD

IMGT

EMBL

AK089835 AK163608 AK172008 CH466531 M28240 M62542 M62551 M62552 M62553 M84372

GenPept

AAA37388 AAA37389 AAA37390 AAA74753 BAC40973 BAE37418 BAE42774 EDL17351