Version 5.4
Mus musculus Protein: Slc52a3
Summary
InnateDB Protein IDBP-209598.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc52a3
Protein Name RIKEN cDNA 2310046K01 gene
Synonyms 2310046K01Rik; RFT2;
Species Mus musculus
Ensembl Protein ENSMUSP00000072961
InnateDB Gene IDBG-209596 (Slc52a3)
Protein Structure
UniProt Annotation
Function Riboflavin transporter. Riboflavin transport is Na(+)- independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), and to a lesser extent by amiloride (By similarity). {ECO:0000250}.
Subcellular Localization Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0032217 riboflavin transporter activity
Biological Process
GO:0007605 sensory perception of sound
GO:0032218 riboflavin transport
GO:0034605 cellular response to heat
Cellular Component
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID MGI:1916948
InterPro IPR009357 Endogenous retrovirus receptor
PFAM PF06237
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D6X5
PhosphoSite PhosphoSite-Q9D6X5
TrEMBL
UniProt Splice Variant
Entrez Gene 69698
UniGene Mm.258262
RefSeq NP_081448
MGI ID
MGI Symbol Slc52a3
OMIM
CCDS CCDS16876
HPRD
IMGT
EMBL AK009850 AK029091 AK154970 AK170158 AL845161 BC016127 CH466551
GenPept AAH16127 BAB26542 BAC26290 BAE32962 BAE41605 CAM17704 CAM17705 EDL05945

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca