Version 5.4
Mus musculus Protein: Nrsn2
Summary
InnateDB Protein IDBP-209717.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nrsn2
Protein Name neurensin 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000078260
InnateDB Gene IDBG-209715 (Nrsn2)
Protein Structure
UniProt Annotation
Function May play a role in maintenance and/or transport of vesicles. {ECO:0000269PubMed:16527258}.
Subcellular Localization Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Disease Associations
Tissue Specificity Expressed specifically in brain where it is widely expressed, with highest levels of expression in thalamus and hypothalamus. In brain, found in neural cell bodies and detected in many regions of the limbic system, such as the septum nucleus, horizontal and vertical limbs of the diagonal band, hippocampus, amygdaloid nucleus, and habernula nucleus. Also localizes to small vesicles found in the perinuclear region of Neuro2a and PC12 cells. {ECO:0000269PubMed:16527258}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0030133 transport vesicle
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID MGI:2684969
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5HZK2
PhosphoSite PhosphoSite-Q5HZK2
TrEMBL
UniProt Splice Variant
Entrez Gene 228777
UniGene Mm.330667
RefSeq NP_001009948
MGI ID
MGI Symbol Nrsn2
OMIM
CCDS CCDS16882
HPRD
IMGT
EMBL AK140190 AL928568 BC088982
GenPept AAH88982 BAE24271 CAM23206

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca