Mus musculus Protein: Hoxb3
Summary
InnateDB Protein IDBP-209913.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hoxb3
Protein Name homeobox B3
Synonyms Hox-2.7;
Species Mus musculus
Ensembl Protein ENSMUSP00000053426
InnateDB Gene IDBG-209909 (Hoxb3)
Protein Structure
UniProt Annotation
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001525 angiogenesis
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0009952 anterior/posterior pattern specification
GO:0021546 rhombomere development
GO:0021615 glossopharyngeal nerve morphogenesis
GO:0030878 thyroid gland development
GO:0048704 embryonic skeletal system morphogenesis
GO:0050767 regulation of neurogenesis
GO:0051216 cartilage development
GO:0060216 definitive hemopoiesis
GO:0060324 face development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:96184
InterPro IPR001356 Homeobox domain
IPR009057 Homeodomain-like
IPR020479 Homeodomain, metazoa
PFAM PF00046
PRINTS PR00024
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P09026
PhosphoSite PhosphoSite-P09026
TrEMBL
UniProt Splice Variant
Entrez Gene 15410
UniGene Mm.342481
RefSeq NP_034588
MGI ID
MGI Symbol Hoxb3
OMIM
CCDS CCDS25299
HPRD
IMGT
EMBL M18168 S35628 U02278 X66177
GenPept AAA08719 AAA37840 AAB60496 CAA46951