Version 5.4
| Mus musculus Protein: Inpp5f | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-210675.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Inpp5f | ||||||||
| Protein Name | inositol polyphosphate-5-phosphatase F | ||||||||
| Synonyms | 5830435P03Rik; AI115354; AW561896; cI-27; mKIAA0966; SAC2; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000045910 | ||||||||
| InnateDB Gene | IDBG-210673 (Inpp5f) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Inositol 5-phosphatase which acts on phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Hydrolyzes phosphatidylinositol 4,5- bisphosphate most effectively. Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | |||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2141867 | ||||||||
| InterPro |
IPR002013
Synaptojanin, N-terminal IPR022158 Inositol phosphatase |
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| PFAM |
PF02383
PF12456 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8CDA1 | ||||||||
| PhosphoSite | PhosphoSite-Q8CDA1 | ||||||||
| TrEMBL | B2RQ14 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 101490 | ||||||||
| UniGene | Mm.490344 | ||||||||
| RefSeq | NP_848756 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Inpp5f | ||||||||
| OMIM | |||||||||
| CCDS | CCDS21899 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK030870 AK034482 AK047166 AK129249 AK150418 BC067200 BC125437 BC137700 CH466531 | ||||||||
| GenPept | AAH67200 AAI25438 AAI37701 BAC27166 BAC28723 BAC32978 BAC98059 BAE29542 EDL17656 | ||||||||