Mus musculus Protein: Tns4
Summary
InnateDB Protein IDBP-210912.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tns4
Protein Name tensin 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000017751
InnateDB Gene IDBG-210910 (Tns4)
Protein Structure
UniProt Annotation
Function May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton May promote apoptosis, via its cleavage by caspase-3. Cytoplasm, cytoskeleton. {ECO:0000250}.
Subcellular Localization Cell junction, focal adhesion {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
GO:0008104 protein localization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005925 focal adhesion
Protein Structure and Domains
PDB ID MGI:2144377
InterPro IPR000980 SH2 domain
IPR006020 PTB/PI domain
IPR013625 Tensin phosphotyrosine-binding domain
PFAM PF00017
PF14633
PF00640
PF14719
PF08416
PRINTS PR00401
PIRSF
SMART SM00252
SM00462
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BZ33
PhosphoSite PhosphoSite-Q8BZ33
TrEMBL
UniProt Splice Variant
Entrez Gene 217169
UniGene Mm.262067
RefSeq NP_766152
MGI ID
MGI Symbol Tns4
OMIM
CCDS CCDS25372
HPRD
IMGT
EMBL AK036834 AK170638 AL591366 BC055820 CH466556
GenPept AAH55820 BAC29598 BAE41928 CAM26976 EDL16179