Version 5.4
Mus musculus Protein: Dsn1
Summary
InnateDB Protein IDBP-211066.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dsn1
Protein Name DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
Synonyms 1700022L09Rik; AW552447;
Species Mus musculus
Ensembl Protein ENSMUSP00000099418
InnateDB Gene IDBG-211062 (Dsn1)
Protein Structure
UniProt Annotation
Function Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Associated with the kinetochore. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0008150 biological_process
GO:0051301 cell division
Cellular Component
GO:0000444 MIS12/MIND type complex
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1914184
InterPro IPR013218 Kinetochore-associated protein Dsn1/Mis13
PFAM PF08202
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CYC5
PhosphoSite PhosphoSite-Q9CYC5
TrEMBL B0QZT5
UniProt Splice Variant
Entrez Gene 66934
UniGene Mm.394343
RefSeq NP_080129
MGI ID
MGI Symbol Dsn1
OMIM
CCDS CCDS16972
HPRD
IMGT
EMBL AK006246 AK017740 AK017813 AL669932 BC025079 BC046807
GenPept AAH25079 AAH46807 BAB24479 BAB30906 BAB30950

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca