Mus musculus Protein: Kat2a
Summary
InnateDB Protein IDBP-211543.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Kat2a
Protein Name K(lysine) acetyltransferase 2A
Synonyms 1110051E14Rik; AW212720; Gcn5; Gcn5l2; mmGCN5;
Species Mus musculus
Ensembl Protein ENSMUSP00000006973
InnateDB Gene IDBG-211539 (Kat2a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 101 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 23 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 101 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0004402 histone acetyltransferase activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
GO:0010484 H3 histone acetyltransferase activity
GO:0043997 histone acetyltransferase activity (H4-K12 specific)
Biological Process
GO:0001701 in utero embryonic development
GO:0001756 somitogenesis
GO:0001843 neural tube closure
GO:0006355 regulation of transcription, DNA-templated
GO:0007399 nervous system development
GO:0008283 cell proliferation
GO:0016573 histone acetylation
GO:0021537 telencephalon development
GO:0022037 metencephalon development
GO:0030901 midbrain development
GO:0035264 multicellular organism growth
GO:0043983 histone H4-K12 acetylation
GO:0044154 histone H3-K14 acetylation
GO:0045722 positive regulation of gluconeogenesis
Cellular Component
GO:0000123 histone acetyltransferase complex
GO:0005634 nucleus
GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex
GO:0030914 STAGA complex
GO:0072686 mitotic spindle
Protein Structure and Domains
PDB ID MGI:1343101
InterPro IPR000182 GNAT domain
IPR001487 Bromodomain
IPR009464 PCAF, N-terminal
IPR016181 Acyl-CoA N-acyltransferase
IPR016376 Histone acetylase PCAF
PFAM PF00583
PF13302
PF13508
PF13673
PF13718
PF00439
PF06466
PRINTS PR00503
PIRSF PIRSF003048
SMART SM00297
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q99KW4
UniProt Splice Variant
Entrez Gene 14534
UniGene Mm.218837
RefSeq NP_001033099
MGI ID
MGI Symbol Kat2a
OMIM
CCDS CCDS25432
HPRD
IMGT
EMBL AK155347 AK155842 AL591469 BC003983 BC063752
GenPept AAH03983 AAH63752 BAE33207 BAE33458