Version 5.4
Mus musculus Protein: Adam8
Summary
InnateDB Protein IDBP-211614.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adam8
Protein Name a disintegrin and metallopeptidase domain 8
Synonyms CD156; CD156a; E430039A18Rik; MS2;
Species Mus musculus
Ensembl Protein ENSMUSP00000026546
InnateDB Gene IDBG-211612 (Adam8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0016337 single organismal cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
Protein Structure and Domains
PDB ID MGI:107825
InterPro IPR000742 Epidermal growth factor-like domain
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR001762 Blood coagulation inhibitor, Disintegrin
IPR002870 Peptidase M12B, propeptide
IPR006586 ADAM, cysteine-rich
PFAM PF00008
PF01421
PF00200
PF01562
PF08516
PRINTS PR00289
PIRSF
SMART SM00181
SM00050
SM00608
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3U7G2
UniProt Splice Variant
Entrez Gene 11501
UniGene Mm.15969
RefSeq NP_001277995
MGI ID
MGI Symbol Adam8
OMIM
CCDS CCDS72064
HPRD
IMGT
EMBL AC107822 AK152675
GenPept BAE31407

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca