Version 5.4
Mus musculus Protein: Bet1l
Summary
InnateDB Protein IDBP-211859.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bet1l
Protein Name blocked early in transport 1 homolog (S. cerevisiae)-like
Synonyms 2610021K23Rik; Gs15;
Species Mus musculus
Ensembl Protein ENSMUSP00000026557
InnateDB Gene IDBG-211857 (Bet1l)
Protein Structure
UniProt Annotation
Function Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). {ECO:0000250UniProtKB:O35152}.
Subcellular Localization Golgi apparatus membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}. Note=Present throughout the Golgi apparatus, with increasing concentration from cis-Golgi to the trans-Golgi face of the stacks. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
Biological Process
GO:0015031 protein transport
GO:0042147 retrograde transport, endosome to Golgi
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005795 Golgi stack
GO:0016020 membrane
GO:0030173 integral component of Golgi membrane
Protein Structure and Domains
PDB ID MGI:1913128
InterPro IPR000727 Target SNARE coiled-coil domain
PFAM PF05739
PRINTS
PIRSF
SMART SM00397
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O35153
PhosphoSite PhosphoSite-O35153
TrEMBL
UniProt Splice Variant
Entrez Gene 54399
UniGene Mm.155696
RefSeq NP_061212
MGI ID
MGI Symbol Bet1l
OMIM
CCDS CCDS21987
HPRD
IMGT
EMBL AF003999 AK011508 AK161239
GenPept AAB66321 BAB27666 BAE36260

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca