InnateDB Protein
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IDBP-212718.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Slc13a3
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Protein Name
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solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000029208
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InnateDB Gene
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IDBG-212716 (Slc13a3)
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Protein Structure
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Function |
High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-5 carbon atoms. The stoichiometry is probably 3 Na(+) for 1 divalent succinate.
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Subcellular Localization |
Cell membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Highly expressed in kidney, and at much lower levels in brain.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
0
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0005215
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transporter activity
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GO:0015362
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high affinity sodium:dicarboxylate symporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2149635
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InterPro |
IPR001898
Sodium/sulphate symporter
IPR004680
Citrate transporter-like domain
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PFAM |
PF00939
PF03600
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q91Y63
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PhosphoSite |
PhosphoSite-Q91Y63
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TrEMBL |
Q3UUJ6
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UniProt Splice Variant |
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Entrez Gene |
114644
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UniGene |
Mm.250738
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RefSeq |
NP_473396
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MGI ID |
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MGI Symbol |
Slc13a3
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OMIM |
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CCDS |
CCDS17081
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HPRD |
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IMGT |
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EMBL |
AF306491
AK138344
BC026803
CH466551
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GenPept |
AAH26803
AAK49898
BAE23629
EDL06463
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