Mus musculus Protein: Adnp
Summary
InnateDB Protein IDBP-213110.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adnp
Protein Name activity-dependent neuroprotective protein
Synonyms AA589558; mKIAA0784;
Species Mus musculus
Ensembl Protein ENSMUSP00000056809
InnateDB Gene IDBG-213108 (Adnp)
Protein Structure
UniProt Annotation
Function Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.
Disease Associations
Tissue Specificity Expressed in the brain, with a higher expression in cerebellum and hippocampus. Weakly expressed in lung, kidney and intestine, and expressed at intermediate level in testis.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0043524 negative regulation of neuron apoptotic process
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1338758
InterPro IPR001356 Homeobox domain
IPR007087 Zinc finger, C2H2
IPR009057 Homeodomain-like
IPR015880 Zinc finger, C2H2-like
PFAM PF00046
PF00096
PRINTS
PIRSF
SMART SM00389
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Z103
PhosphoSite PhosphoSite-Q9Z103
TrEMBL Q8BNY2
UniProt Splice Variant
Entrez Gene 11538
UniGene Mm.201322
RefSeq
MGI ID
MGI Symbol Adnp
OMIM
CCDS CCDS38342
HPRD
IMGT
EMBL AF068198 AK079160 AK129214 BC050833 BC090840 BX005039
GenPept AAD19843 AAH50833 AAH90840 BAC37563 BAC98024